A knee injury has kept the England international out of United's side since August.
But Fergie now says that the 27 year old is fit and ready and will play some part in the Champions League game.
The United boss told reporters: "We've got Ashley Young back and he'll be involved tomorrow. We've got Nani, Antonio Valencia, Ryan Giggs - plenty of wide players. I have an issue in terms of picking the team. Hopefully I get it right.
"Shinji Kagawa didn't play on Saturday so he can prepare for tomorrow. Also, Stoke's a different team to any other side he's played. But mainly it was to give him a rest before tomorrow."