The United pair have been selected in Ireland boss Giovanni Trapattoni's 25-man squad for the two legged affair in Dublin and Paris.
The first leg will take place at Croke Park on Saturday, 14th November and the second leg at Stade de France on Wednesday 18th November.
The winner of the tie over two legs will go through to next year's World Cup finals in South Africa.
Republic of Ireland squad: Given (Manchester City), Westwood (Coventry City), Murphy (Scunthorpe United), O'Shea (Manchester United), Dunne (Aston Villa), Kelly (Fulham), Kilbane (Hull City), Nolan (Preston North End), St Ledger (Middlesbrough), McShane (Hull City), O'Dea (Reading), McGeady (Celtic), Duff (Fulham), Gibson (Manchester United), Whelan (Stoke City), Andrews (Blackburn Rovers), Miller (Hibernian), Hunt (Hull City), Keogh (Wolves), Lawrence (Stoke City), Doyle (Wolves), Keane (Tottenham Hotspur), Long (Reading), Best (Coventry City), Stokes (Hibernian).