The United keeper is believed to have been rested for the game in Spain on Tuesday night with the number one jersey being occupied by either Ben Foster or Tomasz Kuszczak in the Group E match.
Elsewhere, Christiano Ronaldo did travel with the squad even though there were doubts about his fitness after he suffered leg injuries during the weekend match against Aston Villa.
United will definately be without Gary Neville and Dimitar Berbatov who are sidelined with groin and hamstring injuries respectively.
Danny Wellbeck is also sidelined with a groin injury.