Rivals Manchester City are currently two points clear at the top of the table but they have not won the top-flight championship since 1968.
"I think the experience of doing it before with the manager [is key]," said Giggs. "We've got older players who've been there, and younger players who haven't and really want to win things, so hopefully that's in our favour."
United have been the dominant force under Sir Alex Ferguson since the Premier League era began in 1992 with 12 titles, taking their overall tally to a record 19.
And while City are in pole position Giggs thinks United's know-how could be pivotal during the run-in.
"I think in most people's eyes they're favourites because they're top of the league, and because of the quality they've got, and the football they played early-season," the 38-year-old told manutd.com.
"You can't ignore the money and the quality they've got, and their strength in depth.
"They're obviously trying to lay the foundations for 10, 20, 30 years. Whether it happens or not we'll have to wait and see.
"It's just down to which team handles it (pressure) best.
"They've got a lot of experience, they've got players who've won things, but we like to think we've got a good mix of experience and hunger."
Source: PA
Source: PA