Patrice Evra will return after a short trip to France following a family bereavement, Edwin van der Sar will reclaim a starting spot off Anders Lindegaard and Nemanja Vidic, Rio Ferdinand and Rafael are all likely to be given the all-clear after recent injuries.
Dimitar Berbatov also sat out Saturday's FA Cup win at Southampton, although whether Wayne Rooney will partner him in attack in Tuesday's Barclays Premier League match is open to debate given Javier Hernandez has scored in his last two games.
Source: PA
Source: PA