Man City pulled off a lucky win last night at Old Trafford that cuts United's lead at the top of the table down to just twelve points although they have the formality of beating Stoke again at the weekend.
But even though United have a strong advantage over the rest, Fergie has urged his players to put the setback against City to the back of their minds and concentrate fully on getting the ten points that are still needed, starting with the three on Saturday.
He told reporters after the game: "It's a healthy lead but we're not taking anything for granted.
"If you look at our history over the years, we always make it difficult for ourselves.
"The supporters are hanging on the edge of their seats every year. It is a 12-point lead, we go to Stoke at the weekend and we will have a go."